Determinants of Student Performance in an Undergraduate Financial Accounting Class

This study investigates the effects of class size, high school accounting, aptitude and attitude on learning , measured by the difference between post-test and pre-test scores, in an undergraduate financial accounting class, after controlling for students' major and semester level. Statistical analysis showed that scores of students in small classes improved by 48%, while scores of students in the large classes improved by 6% percent, implying a decline in learning by 88% by shifting to larger classes. High school accounting was found to improve pre- and post-test scores but the improvement on their post-test scores was significantly lower, implying a diminishing effect of high school accounting on performance as the complexity of the course material increases. We also found that midterm grade (aptitude) and changes in perception about the relevance of the class on business-related issues (attitude) motivate learning.Teaching/Communication/Extension/Profession,

Fox News: Fair and Balanced? We Report. You Decide.

The Fox News Channel has been claiming for more than a decade that their news channel is fair and balanced. To test this claim a statistical analysis was done on 32 partial transcripts of the Hannity and Colmes Shows posted on the internet with dates from February 16, 2003 to January 7, 2009. Results indicated that there was a statistically significant difference between the average number of words Sean Hannity spoke (397) and the average number of words Alan Colmes spoke (284) on the 32 partial transcripts. Hannity spoke more words than Colmes on 21 of the 32 partial transcripts and this observed frequency approached statistical significance. Based on the data collected from February 16, 2003 to January 7, 2009 the findings suggest that the Hannity and Colmes Show is not fair and balanced and that, by inference, perhaps neither may the Fox News Channel be fair and balanced. The methodology used in this study can be used to analyze a different set of data. Keywords: Media Bias, Fox News, Unfair, Unbalanced, Journalism, Communicatio

Rural subdivisions and local taxes : the fiscal impact of "recreational" and rural residential subdivisions in Klamath County, Oregon

Starting in the 1960's, the demand for recreational properties nationwide experienced a great surge. [Reilly, 1973; David, 1969; Hoover, n.d.; ASPO, 1976] A number of studies have been done of the impact of recreational subdivisions on local taxes. [Tillson, et. al. 1972; Thompson and Myrick, 1975; LeJeune, 1972; Moss and Clonts, 1972; ASPO, 1976; Brown, 1970] These studies generally indicate that such subdivisions tend to be a fiscal boon initially (lowering local residents' taxes) and that at some point in their development they may become a fiscal burden as the number of year-round resident families increases. The present report is a case study of three types of rural subdivisions in Klamath County, Oregon: (1) exurban subdivisions (i.e., rural ranchettes on the fringe of a small town near the urban center of the county); (2) small town fringe subdivisions (i.e., large lot subdivisions on the fringe of a small unincorporated town); and (3) rural "recreational" subdivisions (i.e., large lot subdivisions in an isolated rural area). The report examines the characteristics of these three types of subdivisions and finds them to be similar in terms of the factors affecting fiscal impacts: the rate of residential development, the public services provided, the number of year-round resident families and the proportion of out-of-county owners. The fiscal impacts of the various types of subdivisions are estimated and the factors which explain the differences are identified. The report concludes with some observations about what are being presented to planning commissions as "recreational" subdivisions.Published February 1977. Facts and recommendations in this publication may no longer be valid. Please look for up-to-date information in the OSU Extension Catalog: http://extension.oregonstate.edu/catalo

Planned expenditures of Oregon counties : fiscal year 1975-76

Published November 1976. Facts and recommendations in this publication may no longer be valid. Please look for up-to-date information in the OSU Extension Catalog: http://extension.oregonstate.edu/catalo

PenQuest Volume 1, Number 2

Table of Contents for this Volume: Untitled by Julie Ambrose Night by Judith Gallo Untitled by Judy Gozdur the shamans by Charles Riddles Untitled by Jerry Connell Untitled by Laura Woods Untitled by LEMA Wicked Bird by Laura Jo Last Untitled by Rick Dentos Untitled by Jeni Moody Untitled by Bettie W. Kwibs Untitled by Joann Stagg The Protector Stood by Laura Jo Last Visions of Salome by Charles Riddles Untitled by Thomas Tutten Kennesaw Line by Don Ova-Dunaway Stone Blood by Mary Ellen C. Wofford Untitled by Roger Whitt Jr. Untitled by C. Wingate Untitled by Doug Dorey Untitled by Karen Blumberg Untitled by Beverly Oviatt Untitled by Virginia Shrader The Crapulous Credo of Charles C. by Charles Riddles the brave and the true by David Reed Untitled by Charles Gutierrez Canoe Creek by Patricia Kraft Untitled by Linda Bobinger The Man in the Iron Lung by Patricia Kraft Untitled by Roger Whitt, Jr. Childish Things by Kathleen Gay Untitled by Joseph Avanzini The Lover by Mary S. Aken Untitled by Ann Harrington And He Taketh Away by David Reed Untitled by Mary Graham Untitled by Melody A. Cummons Untitled by Karen Blumberg To The Poets by Judith Gallo Untitled by Ann Harringto

PenQuest Volume 2, Number 1

Table of Contents for this Volume: Untitled by Janet Collins Untitled by Judy Gozdur Last Hour of Light by Susan Reed Untitled by Judy Godzur Untitled by Rick Wagner Untitled by Carol Groover Untitled by R. Wagner Only in the Portico by Linda Banicki Untitled by Helen Hagadorn Private Place, Pubic Place by David Reed Untitled by Tammy Hutchinson Untitled by Tammy Hutchinson Madison Knights by Susan Reed Untitled by Sissy Crabtree The Price by Sandra Coleman Untitled by Ann Harrington Invasion of Privacy by Mark Touchton Untitled by Bruce Warner Untitled by Tom Schifanella Untitled by Tammy Hutchinson Bloodwork by Laura Jo Last Untitled by David Whitsett Burial Instructions by Bill Slaughter Untitled by S. Trevett PenQuest Interview: Joe Haldeman by David Reed Her Name Came from the Sea by Richard L. Ewart Untitled by V. Williams In the Woodshed by R. E. Mallery Untitled by Modesta Matthews Untitled by David Olson Illumination by E. Allen Tilley Untitled by Joseph Avanzini Everywoman by Laura Jo Last Untitled by Beth Goeckel Believe Me by Donna Kaluzniak Untitled by Judy Gozdur Untitled by Judy Gozdur Unicorn by David Reed Untitled by Susan Reed untitled by Paul Cramer Unititled by Lucinda Halsema The Violin by Richard L. Ewart Untitled by Maria Barry Untitled by Roger Whitt Jr. Haiku by Lori Nasrallah Rhymer’s Revolt by R. E. Mallery Untitled by Valerie William

The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer

Abstract: Breast cancer is a common disease partially caused by genetic risk factors. Germline pathogenic variants in DNA repair genes BRCA1, BRCA2, PALB2, ATM, and CHEK2 are associated with breast cancer risk. FANCM, which encodes for a DNA translocase, has been proposed as a breast cancer predisposition gene, with greater effects for the ER-negative and triple-negative breast cancer (TNBC) subtypes. We tested the three recurrent protein-truncating variants FANCM:p.Arg658*, p.Gln1701*, and p.Arg1931* for association with breast cancer risk in 67,112 cases, 53,766 controls, and 26,662 carriers of pathogenic variants of BRCA1 or BRCA2. These three variants were also studied functionally by measuring survival and chromosome fragility in FANCM−/− patient-derived immortalized fibroblasts treated with diepoxybutane or olaparib. We observed that FANCM:p.Arg658* was associated with increased risk of ER-negative disease and TNBC (OR = 2.44, P = 0.034 and OR = 3.79; P = 0.009, respectively). In a country-restricted analysis, we confirmed the associations detected for FANCM:p.Arg658* and found that also FANCM:p.Arg1931* was associated with ER-negative breast cancer risk (OR = 1.96; P = 0.006). The functional results indicated that all three variants were deleterious affecting cell survival and chromosome stability with FANCM:p.Arg658* causing more severe phenotypes. In conclusion, we confirmed that the two rare FANCM deleterious variants p.Arg658* and p.Arg1931* are risk factors for ER-negative and TNBC subtypes. Overall our data suggest that the effect of truncating variants on breast cancer risk may depend on their position in the gene. Cell sensitivity to olaparib exposure, identifies a possible therapeutic option to treat FANCM-associated tumors